Publikationen
2025
Sommer PJ, Schuster S, Goldhardt O, Okamura N, Mueller-Sarnowski F, Scheifele M, Eckenweber F, Kreuzer A, Griessl M, Bartenstein P, Wegehaupt T, Wolski L, Priller J, Rominger A, Beyer L, Grimmer T, Brendel M. Neuroimage Clin. 2025 Apr 24 https://doi.org/10.1016/j.nicl.2025.103789
2024
Dogan V, Taneska M, Novotni G, Iloski S, Novotni A, Dimitrova V, Milutinovic M, Novotni L, Weber A, Joksimkoski B, Chorbev I, Hasani S, Ivanovska A, Grimmer T, Fischer J. Front. Psychiatry. 2024 Oct 01. https://doi.org/10.3389/fpsyt.2024.1421582.
Jessen F, Kramberger MG, Angioni D, Aarsland D, Balasa M, Bennys M, Boada M, Boban M, Chincarini A, Exalto L, Felbecker A, Fliessbach K, Frisoni GB, Garza-Martinez AJ, Grimmer T, Hanseeuw B, Hort J, Ivanoiu A, Klöppel S, Krajcovicova L, McGuinnes B, Mecocci P, de Mendonca A, Nous A, Ousset P-J, Paquet C, Perneczky R, Peters O, Tabuas-Pereira M, Piazza F, Plantone D, Riverol M, Ruiz A, Sacco G, Santana I, Scarmeas N, Solje E, Stefanova E, Sutovsky S, van der Flier W, Welsh T, Wimo A, Winblad B, Frölich L & Engelborghs S. J Prev Alzheimers Dis. 2024 Aug 11. https://doi.org/10.14283/jpad.2024.153.
Wolski L, Bopp AK, Schwientek AK, Langer S, Dogan V & Grimmer T. Z Gerontol Geriat. 2024 Jun 05. https://doi.org/10.1007/s00391-024-02319-y.
Kurz A, Fischer IM, Dogan V, Kurz C. GMS Ger Med Sci. 2024 Apr 24 doi: 10.3205/000331.
Novotni G, Taneska M, Novotni A, Fischer J, Iloski S, Ivanovska A, Dimitrova V, Novotni L, Milutinovic M, Joksimoski B, Chorbev I, Hasani S, Dogan V, Grimmer T, Kurz A. Front. Dement. 2024 Apr 10 doi: 10.3389/frdem.2024.1391471.
2023
Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease(link is external)
Bateman RJ, Smith J, Donohue MC, [...] Grimmer T, [...] GRADUATE I and II Investigators and the
Gantenerumab Study Group. Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease. N Engl J Med. 2023 Nov 16;389(20):1862-1876. doi: 10.1056/NEJMoa2304430. PMID: 37966285; PMCID: PMC10794000.
Menne F, Grimmer T, Schipke CG. Neurodegener Dis Manag. 2023 Oct;13(5):269-280. doi: 10.2217/nmt-2023-0023. Epub 2023 Dec 8. PMID: 38063885.
Osterman A, Krenn F, Iglhaut M,[...] Grimmer T, Durner J, Czibere L, Dächert C, Grzimek-Koschewa N, Protzer U, Kaderali L, Baldauf HM, Keppler OT. Med Microbiol Immunol. 2023 Oct;212(5):307-322. doi: 10.1007/s00430-023-00774-9. Epub 2023 Aug 10. PMID: 37561226; PMCID: PMC10501957.
Finze A, Biechele G, Rauchmann BS, [...] Goldhardt O, Grimmer T [...] Levin J, Perneczky R, Brendel M. Mol Psychiatry. 2023 Oct;28(10):4438-4450. doi: 10.1038/s41380-023-02188-8. Epub 2023 Jul 26. PMID: 37495886; PMCID: PMC10827660.
Irrelevant interests? A qualitative study into how German family surrogates of persons living with dementia fulfill their legal role as advocates of an advance directive(link is external)
Fischer J, Roßmeier C, Hartmann J, Riedl L, Tensil M, Diehl-Schmid J, Jox RJ. The Gerontologist, gnad119. 2023 Aug. doi: 10.1093/geront/gnad119.
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease(link is external)
European Alzheimer’s & Dementia Biobank Mendelian Randomization (EADB-MR) Collaboration; Luo J, Thomassen JQ, Bellenguez C, [....] Grimmer T [...] Ramirez A, Lambert JC, Frikke-Schmidt R.
JAMA Netw Open. 2023 May 1;6(5):e2313734. doi: 10.1001/jamanetworkopen.2023.13734.
Erratum in: JAMA Netw Open. 2023 Jun 1;6(6):e2321189. doi: 10.1001/jamanetworkopen.2023.21189. PMID: 37195665; PMCID: PMC10193187.
Anti-amyloid antibody therapies in Alzheimer's disease(link is external)
Perneczky R, Jessen F, Grimmer T, Levin J, Flöel A, Peters O, Froelich L. Brain. 2023 Mar
1;146(3):842-849. doi: 10.1093/brain/awad005. PMID: 36655336.
Rus T, Perovnik M, Vo A, Nguyen N, Tang C, Jamšek J, Šurlan Popović K, Grimmer T, Yakushev I, Diehl-Schmid J, Eidelberg D, Trošt M. Hum Brain Mapp. 2023 Feb 15;44(3):1079-1093. doi: 10.1002/hbm.26140. Epub 2022 Nov 5. PMID: 36334269; PMCID: PMC9875921.
Grazia A, Altomare D, Preis L, Monsch AU, Cappa SF, Gauthier S, Frölich L, Winblad B, Welsh-Bohmer KA, Teipel SJ, Boccardi M; . Alzheimers Dement.
2023 Jun;19(6):2276-2286. doi: 10.1002/alz.12830. Epub 2022 Dec 1. Erratum in:
Alzheimers Dement. 2024 Jan;20(1):752. doi: 10.1002/alz.13531. PMID: 36453876.
2022
Herpes simplex virus alters Alzheimer´s disease biomarkers - A hypothesis paper(link is external)
Goldhardt O, Freiberger R, Dreyer T, Wilner L, Yakushev I, Ortner M, Förstl H, Diehl-Schmid J, Milz E, Priller J, Ramirez A, Magdolen V, Thaler M, Grimmer T. Alheimers Dement. 2022 Nov 17 doi: 10.1002/alz.12834.
Cognitive impairment and microvascular function in end-stage renal disease. (link is external)
Mapping covariance in brain FDG uptake to structural connectivity. (link is external)
Decoupling of regional neural activity and inter-regional functional connectivity in Alzheimer's disease: a simultaneous PET/MR study. (link is external)
2021
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. (link is external)
Intepirdine as adjunctive therapy to donepezil for mild-to-moderate Alzheimer's disease: A randomized, placebo-controlled, phase 3 clinical trial (MINDSET). (link is external)
Age-Dependency of Total Tau in the Cerebrospinal Fluid Is Corrected by Amyloid-β 1-40: A Correlational Study in Healthy Adults. (link is external)
2020
Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey. (link is external)
Biomarker Testing: Piercing the Fog of Alzheimer's and Related Dementia. (link is external)
Value of a Panel of 6 Serum Biomarkers to Differentiate Between Healthy Controls and Mild Cognitive Impairment Due to Alzheimer Disease. (link is external)
Correction:18F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases. (link is external)
Integrity of Neurocognitive Networks in Dementing Disorders as Measured with Simultaneous PET/Functional MRI. (link is external)
Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. (link is external)
Regional Cerebral Associations Between Psychometric Tests and Imaging Biomarkers in Alzheimer's Disease. (link is external)
Therapeutic Drug Monitoring of Rivastigmine and Donepezil Under Consideration of CYP2D6 Genotype-Dependent Metabolism of Donepezil. (link is external)
Variability of clinical syndromes and cerebral glucose metabolism in symptomatic frontotemporal lobar degeneration associated with progranulin mutations. (link is external)
Serum Concentrations of Cholinesterase Inhibitors in Patients With Alzheimer's Dementia Are Frequently Below the Recommended Levels. (link is external)
The overnight reduction of amyloid β 1-42 plasma levels is diminished by the extent of sleep fragmentation, sAPP-β, and APOE ε4 in psychiatrists on call. (link is external)
Different CSF protein profiles in amyotrophic lateral sclerosis and frontotemporal dementia with C9orf72 hexanucleotide repeat expansion. (link is external)
Normative brain volume reports may improve differential diagnosis of dementing neurodegenerative diseases in clinical practice. (link is external)
Targeted Mass Spectrometry Suggests Beta-Synuclein as Synaptic Blood Marker in Alzheimer's Disease. (link is external)
Correction to: Amyloid PET, FDG-PET or MRI? - the power of different imaging biomarkers to detect progression of early Alzheimer's disease. (link is external)
2018
18F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases. (link is external)
A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease. (link is external)
Functional Decline in Alzheimer's Disease: A Continuum. (link is external)
Rate of β-amyloid accumulation varies with baseline amyloid burden: Implications for anti-amyloid drug trials. (link is external)
Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia. (link is external)
Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer's disease: results of a randomized, double-blind, placebo-controlled phase 2a study. (link is external)
Serum neurofilament light chain in behavioral variant frontotemporal dementia. (link is external)
A multivariate metabolic imaging marker for behavioral variant frontotemporal dementia. (link is external)
An Explorative Note on Apraxia Tests. (link is external)
Plasma levels of soluble amyloid precursor protein β in symptomatic Alzheimer's disease. (link is external)
Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease. (link is external)
Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach. (link is external)
Sex Differences in Neuropsychological Test Performance in Alzheimer's Disease and the Influence of the ApoE Genotype. (link is external)
Step by Step: Kinematics of the Reciprocal Trail Making Task Predict Slowness of Activities of Daily Living Performance in Alzheimer's Disease. (link is external)
Fluid biomarker agreement and interrelation in dementia due to Alzheimer's disease. (link is external)
Cognitive Impairment is Associated with Mortality in Hemodialysis Patients. (link is external)
Increasing Diagnostic Accuracy of Mild Cognitive Impairment due to Alzheimer's Disease by User-Independent, Web-Based Whole-Brain Volumetry. (link is external)
Cerebrospinal Fluid BACE1 Activity and sAβPPβ as Biomarker Candidates of Alzheimer's Disease. (link is external)